Biodesign News

Grant to Advance Supercomputing for Human Health


Local teachers and students participate in Arizona’s largest summer high school bioscience internship program


Arntzen to give lecture at the American Phytopathological Society


Overview

Since its inception in 2002, scientists in the Center for Evolutionary Functional Genomics (EFG) have leveraged innovations in information technology into tools for testing long-standing biological problems. The recent ability to obtain the complete DNA sequence information of any organism, or genome, has allowed us to map and explore the genetic blueprints necessary for life as well as their evolution. We are developing new methods for exploring the gene interactions that guide the maturation of a single fertilized egg cell into a complex adult animal with trillions of cells and building easy-to-use computer software for the analysis of genomic databases. Using developmental gene expression image data from Drosophila, we are developing the first-of-a-kind computational tool and web resource for the digital analysis of developmental gene expression patterns. Read More »

Center News

ASU research team working to decode TB

Thousands of new cases of tuberculosis are reported in the United States every year, making the disease an enduring menace. Three ASU researchers are among those trying to decipher the origins of Mycobacterium tuberculosis, the bacteria responsible for TB. They are making strides to establish a credible evolutionary timeline to better understand the disease. Read More »

Big Buzz: Landmark fruit fly DNA study advances genetics

In a set of papers published in the journal Nature, the Biodesign Institute’s Sudhir Kumar, along with colleagues Alan Filipski, Sonja Prohaska and Stuart Newfeld, participated in the largest comparative DNA analysis of higher organisms ever assembled. In all, the complete DNA sequences, or genomes, from a dozen different fruit fly species were assembled to understand the differences between species at the DNA level. Read More »

“The EFG is building a leading research program at the interface of genomics and bioinformatics that emphasizes the development of methods, technologies, and tools for analyzing genome sequence and functional genomics data. Using novel comparative genomics and gene expression approaches, we are formulating biological hypotheses and addressing them using large-scale datasets.”

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