Chaput Lab: Publications

2009

L.A. Stearns, R. Chhabra, J. Sharma, Y. Liu, W.T. Petuskey, H. Yan, and J.C. Chaput. 2009. Template-Directed Nucleation and Growth of Inorganic Nanoparticles on DNA Scaffolds. Angew. Chem. Int. Ed.  In Press.

S. Lin, D.P. Horning, J.W. Szostak, and J.C. Chaput. 2009. Conformational Analysis of DNA Repair Intermediates by Time-Resolved Fluorescence Spectroscopy. J. Phys. Chem. In Press.

C.R. Simmons, J.M. Stomel, M.D. McConnell, D.A. Smith, J.L. Watkins, J.P. Allen, and J.C. Chaput. 2009. A Synthetic Protein Selected for Ligand Binding Affinity Mediates ATP Hydrolysis. ACS Chem. Biol. 4, 649-658.

E. O. McCullum and J. C. Chaput. 2009. Transcription of an RNA Aptamer by a DNA Polymerase. Chem. Comm. 2938-2940.

B.A.R. Williams, L. Lin, S.M. Lindsay, and J.C. Chaput. 2009. Evolution of a Histone H4-K16 Acetyl-Specific DNA Aptamer.  J. Am. Chem. Soc. 131, 6330-6331.

2008

Zhang, S., McCullum, E., and Chaput, J.C. 2008. Synthesis of Two Mirror Image 4-Helix Junctions Derived from Glycerol Nucleic Acid. J. Am. Chem. Soc. 130, 5846-5847.

Watkins, J. and Chaput, J.C. 2008. Searching Combinatorial Libraries for Native Proteins with Novel Folds. ChemBioChem. 9, 1361-1363.

Chaput, J.C., Woodbury, N.W., Stearns, L.A., and Williams, B.A.R. 2008. Creating protein biocatalysts as tools for future industrial applications. Expert Opin. Biol. Ther. 8, 1087-1098.

 

2007

Williams, B.A.R., Lund, K., Liu, Y., Yan, H. and Chaput, J.C. 2007. Self-Assembled Peptide Nanoarrays: A New Approach to Studying Protein-Protein Interactions. Angewandte Chemie International Ed. 46, 3051-3054.

Smith, M.D., Rosenow, M.A., Wang, M., Allen, J.P., Szostak, J.W. and Chaput, J.C. 2007. Structural Insights into the Evolution of a Non-Biological Protein: Importance of Surface Residues in Protein Fold Optimization. PLoS ONE, 2, e467.

Mansy, S.S., Zhang, J., Kummerle, R., Nilsson, M., Chou, J.J., Szostak, J.W., and Chaput, J.C. 2007. Structure and Evolution of a Non-Biological ATP Binding Protein. J. Mol. Biol. 371, 501-513.

Yang, Y-W., Zhang, S., McCullum, E., and Chaput, J.C. 2007. Experimental Evidence that GNA and TNA are not Sequential Polymers in the Prebiotic Evolution of RNA. J.Mol.Evol. 65, 289-295.

Lin, L., Hom, D., Lindsay, S.M., and Chaput, J.C. 2007. In Vitro Selection of Histone H4 Aptamers for Recognition Imaging Microscopy. J. Am. Chem. Soc. 129, 14568-14569.

 

2005

Horhota, A., Keyong, Z., Ichida, J.K., McLaughlin, L.W., Szostak, J.W. and Chaput, J.C. 2005. Kinetic Analysis of an Efficient DNA-Dependent TNA Polymerase. J. Am. Chem. Soc. 127, 7427-7434.

Nilsson, M., Stomel, J., and Chaput, J.C. 2005. Evolutionary Optimization of a De Novo Selected ATP Binding Protein. Biopolymers 80, 592.

 

2004

Chaput, J.C. and Szostak, J.W. 2004. Evolutionary Optimization of a Non-Biological ATP-Binding Protein for Improved Folding Stability. Chemistry & Biology. 11, 865-874.

 

2003

Chaput, J.C., Ichida, J.K. and Szostak, J.W. 2003. DNA Polymerase-Mediated DNA Synthesis on a TNA Template. J. Am. Chem. Soc. 125, 856-857.

Chaput, J.C. and Szostak, J.W. 2003. DNA Polymerase-Mediated TNA Synthesis. J. Am. Chem. Soc. 125, 9274-9275.

 

2002

Chaput, J.C., Sinha, S. and Switzer, C. 2002. 5-Propynyluracil • diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA. Chem. Comm. 1568-1569.

 

2000

Rice, K.P., Chaput, J.C., Cox, M.M. and Switzer, C. 2000. RecA Protein Promotes Strand Exchange with DNA Substrates Containing isoGuanine and 5-Methyl isoCytosine. Biochemistry 39, 10177-10188.

Chaput, J.C. and Switzer, C. 2000. Non-enzymatic Oligomerization on Templates Containing Phosphodiester-Linked Acyclic Glycerol Nucleic Acid Analogues. J. Mol. Evol. 51, 464-470.

Chaput, J.C. and Switzer, C. 2000. Non-enzymatic Transcription of an isoG:isoC Base Pair. J. Am. Chem. Soc. 122, 12866-12867.

 

2001

Chaput, J.C. and Switzer, C. 2001. Probing DNA Structure and Function with Alternative Nucleic Acids Bearing 2’,5’-Linked, Zwitterionic and iso-Cytosine • iso-Guanine Components. Methods: A Compendium to Methods in Enzymology 23, 141-148.

 

1999

Chaput, J.C. and Switzer, C. 1999. A DNA Pentaplex Incorporating Nucleobase Quintets. Proc. Natl. Acad. Sci. USA 96, 10614-10619.

 

1998

Roberts, C., Chaput, J.C. and Switzer, C. 1998. Beyond Guanine Quartets: Cation-Induced Formation of Homogeneous and Chimeric DNA Tetraplexes Incorporating iso-Guanine and Guanine. Chemistry & Biology 4, 899-908.